Clinical Studies Ingredients
- HgH Amino Acids Blend

These Research Studies on the Ingredients
Prove that GHR Platinum Supplements Really Work

Dr. LE Dorman, MD - Growth Hormone / Amino Acid Blend
Author of "The Methusaleh Factor"

"As we age, our body stops producing an adequate supply of HGH amino acids. Out of the 191 amino acids in the Growth Hormone chain, GHR Platinum replenishes the body with the needed blend of Stacked HGH Amino Acids in the Right Ratio and Molecular Weight that helps stimulate and restore the release of your body’s own natural Growth Hormone. Many substances stimulate the release of Growth Hormone from the pituitary gland. Amino acids, drugs and exercise are among the provocateurs." ( Page 35 )

AMINO ACID: ARGININE

The Amino Acid - ARGININE works in two key ways in the body:

First, it is a precursor used to make other compounds. The first of these functions is that it works by converting into the special compound Nitric Oxide. This substance plays a pivotal role in various activities of metabolism in the body. These include the management of the flow of blood, various cellular activities of the Mitochondria to produce energy, and sending communication signals between the cells.

Nitric Oxide works by dilating and relaxing blood vessels. So it functions as a Vasodilator. This improves the circulation of the blood throughout the whole body. This allows more necessary nutrients from food and supplements, along with oxygen in the blood to reach the many organs, muscles, tissues and cells. This function also helps to lower high blood pressure. As a result of these activities, ARGININE  helps support a healthy Heart Function. Thus, it can be beneficial in alleviating related conditions, including Hypertension, diseases of the circulatory system, angina and Erectile Dysfunction ( ED ).

Meanwhile, Nitric Oxide also assists the body, by helping to remove toxic waste products from both the Liver and the muscles, which are produced from metabolism. Specifically, these include Lactate and Ammonia. The result of removing these waste substances quickly is that it helps the muscles, and the whole body, to recover more rapidly from physical exercise and strenuous workouts.

Second, ARGININE helps the body to create proteins. Additionally, it helps support a healthy Immune System function. Furthermore, it is also used to break-down sugars ( glucose ). Therefore, it might help improve a condition called Insulin Sensitivity. There are some research studies which indicate that it might then be beneficial to help people who suffer from Pre-Diabetes and Type 2 Diabetes.

One of the symptoms of aging is that our bodies sometimes do not create enough Arginine. Or our bodies simply
do NOT produce it very well. Often it is necessary for older people to obtain more Arginine by using supplements.

There have been numerous clinical studies by scientists over the past thirty years, regarding the Amino Acids of ARGININE
and LYSINE. They repeatedly show that increasing the amounts of these two particular amino acids boosts the production of
Growth Hormone ( GH ) and then its release into the body. Both of these amino acids are included in the GHR Platinum
Hgh Releasers products. Here are some of these studies which prove that ARGININE is a Growth Hormone Releaser ( GHR ).

Growth Hormone Responses to Varying Doses of Oral Arginine

Scott R Collier; Darren P Casey; Jill A Kanaley

This research study showed that small amounts of ARGININE ( 5 and 9 grams ) can stimulate a significant increase in Growth Hormone.

Growth Hormone, Arginine and Exercise

Jill A Kanaley  Author ( Department of Exercise Science, Syracuse University, Syracuse, New York, USA )

The author - researcher of this study made the conclusion that most studies involving ARGININE show that this amino acid alone will boost resting Growth Hormone levels by as much as 100% or more.

Acute Effect of Amino Acid Ingestion and Resistance Exercise
on Plasma Growth Hormone Concentration in Young Men

R R Suminski; R J Robertson; F L Goss; S Arslanian; J Kang; S DaSilva; A C Utter; K F Metz

( Human Performance Laboratory, University of Houston, TX 77204 )

In this study, sixteen men completed four separate trials, each randomly chosen.

First they ingested a placebo and did some resistance exercise.

Then they took a dosage of 1,500 mg of the amino acid ARGININE and 1,500 mg of Lysine and performed the very same exercise.

Next they consumed the same two amino acids, with the same amounts, but did no exercise.

Finally they ingested a placebo and again did no exercise.

The researchers measured the results. Concentrations of Growth Hormone ( GH ) were higher at intervals of 30, 60, and 90 minutes during the two exercise trials, compared with the two resting trials ( no exercise ). They did not observe any differences in the levels of Growth Hormone between the exercise trials.

They concluded that taking the two amino acids just before the young men did the resistance exercises, did not affect exercise-induced increases in Growth Hormone.

However, when the two specific amino acids were consumed together in basal conditions, there was a sharp increase in secretion ( release ) of Growth Hormone.

A Study of Growth Hormone Release in Man
After Oral Administration of Amino Acids

A Isidori, A Lo Monaco, M Cappa

This clinical study had 15 male volunteers. The researchers evaluated the factors affecting secretion of growth hormone following consumption of oral amino acids.

The test results showed that using the combination of two specific amino acids ( 1,200 mg Lysine and 1,200 mg ARGININE ) stimulated a release of Pituitary Somatotropin { related to GH } and Insulin.

The researchers concluded that this biological affect in the increase in natural HgH appeared to be due to the use of these two specific amino acids working together.

Increased Human Growth Hormone Following Oral Consumption
of an Amino Acid Supplement: Results of a Randomized,
Placebo-Controlled, Double-Blind, Crossover Study in Healthy Subjects

Charmaine S Tam; William D Johnson; Jennifer Rood; Amy L Heaton; Frank L Greenway

This was a Randomized, Placebo-Controlled, Double-Blind, Crossover Study that involved 16 people ( 12 males and 4 females ). They aged in range about 32 years old ±14 years ). All were healthy adults. At the start of the study, the researchers asked themselves whether certain amino acid supplements ( Arginine and Lysine ) can affect release of HgH.

In this clinical trial, all of the participants received both a placebo and the specific amino acid supplement after an overnight fast. The order of treatment was random. And each application of the dosage was separated by a "washout period" of one week.

Here are the results of their findings. They tested the change in HgH from the time of taking the supplement ( baseline ) to two hours later. By that time, the levels of HgH had been elevated by 682%. Thus they were dramatically increased in comparison with those who took the placebo.

The researchers concluded that a single dosage of the amino acid supplement given was sufficient to significantly raise Growth Hormone levels in healthy men and women. Additionally, they wrote that it is well-established that intravenous application of these specific amino acids ( primarily ARGININE, LYSINE & Orthinine ) produces increased levels of HgH release in significant amounts.

AMINO ACID: LYSINE

L-LYSINE is one of the eight ( 8 ) "Essential" Amino Acids. These are those which our bodies are not able to make. Thus we have to get them from protein foods we eat. Or we have to obtain them from supplements that contain them in forms which our bodies can readily digest and use.

Lysine is one of the critical amino acids which is needed to make the other proteins in the body. It is vital to create muscle tissues, and to produce hormones, enzymes and anti-bodies. It also plays a vital role in the absorption of the mineral Calcium, while it helps to reduce the loss of calcium in urine. It also lowers levels of Cholesterol.

Like the amino acid GLUTAMINE, it also assists in healing and repairing of body tissues and cells and recovery from wounds. As a Binding Agent, it works to help increase the number of new cells in a wound that is healing. Together with the amino acid GLYCINE, it is also required to create Collagen, which is used to form hair strands, skin, nails and the various connecting tissues in the body.

It is a precursor to L-Carnitine, derived from amino acids, and found in most of the cells in the body. This is important for the proper functioning of the Nervous System. Lysine is also a precursor for the compound L-Carathine which is also necessary to maintain a healthy nervous system function.

Carnitine transports Long-Chain Fatty Acids across the cells Mitochondria and then burns them to produce usable energy for metabolism. Afterwards it eliminates the toxins produced by the metabolic processes out of the cells. Lysine is also vital for normal physical growth. Thus, a deficiency in the amount of Lysine in the body can cause various health problems and conditions, including slow physical growth, nausea, dizziness and fatigue.

Many of the research studies testing the amino acid Arginine also include examining the usage of the amino acid LYSINE 
as well. Thus, they are sometimes used together in a particular research trial, as seen in several of the studies already
presented above. And the results of these scientific tests have repeatedly shown and proven, that consumption of
more of both Arginine and LYSINE can stimulate an increase in Growth Hormone levels in the human body.

AMINO ACID: GLUTAMINE

GLUTAMINE is a vital amino acid that supports healthy brain function. It is needed for the creation of both RNA and DNA. Growth hormone stimulates a process in the body which is known as "NeuroGenesis". This is the way in which new neuron cells in the brain are made. It also supports the maintenance and functioning of existing brain cells.

In a similar way, the levels of Growth Hormone also affect the levels of NeuroTransmitters in the brain. These are critical for many functions, processes and activities in the body. In particular, Gluatmine is a powerful amino acid that is a precursor for the making of the NeuroTransmitters GABA and Glutamate. These Neuro-Transmitters also help to regulate and support various cognitive functions, such as mood, concentration and memory. GABA is included in the formulas of GHR Platinum products in the HgH Enhancers Complex.

Researchers know that even small dosages of supplementing with extra GLUTAMINE can stimulate a noticeable increase in the levels of Growth Hormone in the body. Various clinical studies have shown that using even just 2 mg of this powerful amino acid could temporarily raise the levels of Human Growth Hormone ( HGH ) by as much as 78%.

GLUTAMINE is also precursor to making the amino acid ARGININE - which is proven clinically to promote the increase in production and secretion of Growth Hormone ( GH ) in the Pituitary Gland. So when you consume more proteins which contain Glutamine, or you increase your intake with supplements, you allow your body to raise the levels of ARGININE and the NeuroTransmitters GABA and Glutamate. And there are many research studies which have already shown that both Arginine and Glutamine stimulate the release of Growth Hormone.

How does Glutamine work to promote a release of the Growth Hormone? The NeuroTranmitter Glutamate has a significant part in stimulating the Somatotrophs in the Pituitary Gland. These are the special cells in the Pituitary that actually signal the production and secretion ( release ) of Growth Hormone.

There is also a link between Fat Burning in the body and Growth Hormone. Growth Hormone helps in the breaking-down of body fats, by a process that is called "Lipolysis". This is how fats and other lipids are digested and then converted to Fatty Acids. There is also a similar connection between the metabolism of carbohydrates and Growth Hormone. This has a direct relationship to levels of blood sugar levels. Thus Glutamine plays a significant role in the digestive function and also the subsequent conversion of starches, sugars and fats into usable energy through healthy activities of body metabolism.

Since this important amino acid has a significant affect on levels of body fat, sugar and weight loss, it is important to maintain adequate  levels of both Glutamine ( and Arginine ). Both of these amino acids are involved in stimulating the production and release of your own natural Growth Hormone. The result provides various health benefits to our bodies and minds, physically and mentally.

Moreover, improving the metabolism of both carbohydrates and fats in the body, you can achieve healthy weight loss, or simply keep a proper and healthy weight balance. The results will then cause a corresponding increase in the production and release of ( more of ) your own Human Growth Hormone ( HGH ). What is the connection between body fat and HgH levels in the body?

Research studies repeatedly indicate and prove that high levels of BODY FAT, especially BELLY FAT, will decrease, or inhibit, both the production and then the release of Growth Hormone. The amount of fat ( Adipose Tissue ) that men and women carry around in their bodies, especially in their bellies, significantly impacts the production of Growth Hormone in a negative way that is made and released from their Pituitary Glands. So if you can lose that extra weight, particularly any belly fat, you can then actually raise the production and release of more of your HGH. The GHR Platinum products can help you to do just that.

Glutamine is also the most abundant amino acid which is in the blood and in fluids of the body. It has several important functions. It is used to create proteins, produce energy, and help with detoxification and removal of waste products, such as Ammonia, from metabolism.

Additionally, this amino acid is needed for both a healthy digestive function ( as explained above ) and good intestinal health. It also supplies energy for White Blood Cells and for growth and maintenance of certain cells in the Intestines. There, this amino acid helps to maintain the barrier which is between the inside of the intestines and the rest of the body. In this way, it enables you to maintain a healthy gut. This protects against getting what is called a "Leaky Gut". So it works to support a healthy Immune System function, which helps to protect you from infection, sickness and disease.

Deficiencies of this amino acid can occur when a person is experiencing a lot of stress, or has an illness or severe injury. In those times, the body actually needs an abundant supply of Glutamine for healing and recovery from wounds. Specifically, the body requires it for repairing damaged tissues and cells. Consequently, if the body needs more Glutamine than it can make on its own, it must get it elsewhere. As a result, the body might then break down muscle proteins, in order to release more of this amino acid. This is what happens often times when a person gets sick or injured.

When a person is under high levels of stress, the body produces much more the hormone Cortisol. This is the reason that it is called the "Stress Hormone". Is there a link between HgH levels in the body and stress? Health researchers have discovered that Cortisol can inhibit the production of growth hormone. Therefore, when you lower the amount of stress you have in your body, with sufficient amounts of Glutamine, you can also reduce the levels of Cortisol which block the production and release of that very growth hormone you need and want.

Here is one research study that shows an increase of GLUTAMINE causes an increase in Growth Hormone levels:

Increased Plasma Bicarbonate & Growth Hormone After Oral Glutamine Load

T C Welbourne ( Department of Physiology, Louisiana State University College of Medicine, Shreveport, LA 71130 )

In this research trial, a load of Glutamine was given to 9 healthy participants. The goal was to evaluate the effect on levels of plasma Glutamine, bicarbonate, and circulating Growth Hormone.

What was the outcome of the study? The results demonstrated that even a small amount of the amino acid Glutamine can boost alkaline ( bicarbonate ) levels in the body, along with that of Human Growth Hormone.

AMINO ACID: GLYCINE

L-GLYCINE is the second most common amino acid that is used to make the various proteins of the body. It is the most abundant amino acid needed to create Collagen. Collagen is needed for the hair, nails, skin and various connective tissues throughout the body. This amino acid also assists in building bones, muscles ( and energy in the muscles, ) supporting a healthy brain function, as well as supporting healthy patterns of sleep.

Glycine is used to synthesize the TriPeptide Glutathione ( which is an AntiOxidant found in the cells ). This compound is made from the 3 amino acids: Glutamic Acid, Cysteine, and Glycine. But as we age, our bodies have less of an ability to make this important AntiOxidant. Therefore, we most likely we need to obtain more of it by taking supplements as we grow older.

The AntiOxidant Glutathione helps the body to prevent damage and disease to tissues, cells and the organs ( particularly the Liver ), which Free Radicals can cause. When damaged portions of the Liver form Fibrous Tissues, they can become scarred. Or the Liver can become diseased through build-up of excessive fat ( "Fatty Liver" ), alcohol consumption and various immune attacks.

Glycine also works as a brain NeuroTransmitter. In this function, it works in the processing of motor and sensory information, which enables movement, vision and hearing. It also works by helping to calm the central nervous system. And just like the amino acid  Glutamine, the ability of our bodies to make it, can become negatively impacted during times of stress, sickness or injury. Therefore, it is necessary to help repair tissues and cells and for healing of wounds.

Finally, this amino acid participates in the digestive process. It helps to digest fats by managing the release of Bile Acids from the Gall-Bladder into the Small Intestine. At the same time, it also works as a "Glucogenic Amino Acid", that enables the Liver to convert it into glucose ( sugar ).

There have been numerous clinical studies that prove the connection between increasing the amount of Glycine in the body and a related boost in the levels of Human Growth Hormone ( HgH ) in the body. Here are some of them:

Glycine Stimulated Growth Hormone Release in Man

K. Kasai; H. Suzuki; T. Nakamura; H. Shiina; S I Shimoda

In this study, the researchers investigated the affect of administering several different dosages of Glycine on the activities of the Pituitary Gland. The participants were given 4, 8 or 12 grams of the amino acid during a time period of 15 to 30 minutes.

What was the result of their clinical trial? The dose of just 4 or 8 grams of Glycine stimulated a noticeable increase in Growth Hormone levels. And then the application of 12 grams of this amino acid induced a far greater boost in serum levels of GH.

The scientists concluded from their findings that the amino acid Glycine might have a significant part in the functions of the Hypothalamus and Pituitary Glands.

Stimulatory Effect of Glycine on Human Growth Hormone Secretion

K. Kasai; M. Kobayashi; S I Shimoda

This research trial involved 31 adults. Of these, 19 were normal subjects, who were not obese. The other 12 had partial gastrectomy. The amino acid Glycine ( 250 mL ) was given to all of them. In the normal subjects, the researchers noted an obvious and significant increase of the level of serum Human Growth Hormone.

The results of the test showed that Glycine stimulates the Pituitary Gland to secrete Growth Hormone.

The Effect of Glycine Administration on the Characteristics
of Physiological Systems in Human Adults: A Systematic Review

Janjira Soh; Shivaanishaa Raventhiran; Jasinda H Lee; Zi Xiang Lim; Jorming Goh; Brian K Kennedy; Andrea B Maier

The researchers stated that decline of physiological functions in the body during aging leads to what is known as age-related diseases. At the same time, the amino acid Glycine can help increase healthy lifespans. Moreover, it might even reduce inflammation, which is often associated with, and a cause of, such diseases.

Their review was intended to gather the findings, evidence and conclusions of various research tests and trials involving Glycine. They wanted to summarize the affects that this amino acid had demonstrated in 11 physiological bodily systems in adult men and women.

These are their conclusions: The nervous system showed the most positive health effects. This included improved cognitive ( mental )  symptoms from longer-term use of Glycine. At the same time, it also improved sleep patterns in healthy adults.

Reduced Plasma Glycine Concentration in Healthy and Chronically Diseased
Older Adults: a Marker of Visceral Adiposity?

Lars Nj Deutz; Raven A Wierzchowska-McNew; Nicolaas Ep Deutz; Mariëlle Pkj Engelen

( Center for Translational Research in Aging and Longevity,
Department of Kinesiology and Sport Management, Texas A&M University, College Station, TX )

Before the start of this clinical trial, the researchers noted the following: Prior studies involving Glycine have demonstrated that reduced levels of this amino acid are associated with obesity. But the reason or mechanism of that is not yet established.

The goal of this study was to investigate whether such lower amounts of Glycine in older subjects are connected with ( visceral ) Adiposity { condition of being Fat }, age, sex, presence of chronic disease and glucose intolerance. Additionally, it was to determine if , and whether they are caused by a reduced Glycine Whole-Body Production ( WBP ) and/or increased GLY disposal capacity."

The researchers gathered 102 older adults ( 47 mens and 55 women ). They evaluated both body composition, as well as visceral Adipose Tissue ( VAT ). There was clearly a strong link between lower plasma levels of Glycine and increased Visceral Adiposity Tissue mass. Moreover, it was independent of their age, gender, body weight, lean mass or body mass index ( BMI ), and the presence of COPD.

As a result, they concluded the following: Lower plasma levels of Glycine in older people is an indication of Visceral Adiposity, regardless of their age, gender, body composition, existence of any chronic disease and certain other factors.

AMINO ACID: TYROSINE

The amino acid TYROSINE is made from Phenylalanine, one of the 8 "Essential" Amino Acids. Therefore, we must consume plenty of Phenylalanine in our diets, or else we have to obtain it from taking supplements. Thus, if we are lacking in Phenylalanine, we will also be deficient in Tyrosine also.

Tyrosine plays a part in building proteins. In this way, it participates in the production of the various Thyroid hormones ( Thyroxin ), which help regulate metabolism, adreno-cortical hormones, Melanin ( a pigment found in the hair, skin and iris of the eyes ), enzymes,  and various NeuroTransmitters in the brain.

The NeuroTransmitters in our brains relate to our various cognitive abilities, such as mood, focus, concentration, memory, working memory, cognitive flexibility ( ability to switch tasks or change thoughts ) and following instructions.

Thus this amino acid is a precursor for the NeuroTransmitters / Hormones - Dopamine, Epinephrine, Norepinephrine, Adrenaline and Noradrenaline. Each of these compounds can affect the secretion of HgH in the pituitary gland.

Dopamine is critical for our mental functioning and mood. It regulates the reward and pleasure centers. This important
brain substance is also vital for memory and motor skills.

Adrenaline and Noradrenalin are hormones that are responsible for what is called the "Fight-or-Flight Response" in stressful situations. They enable our bodies to stand and fight, or flee and run - from a perceived or actual attack or harm.

In these ways, this particular amino acid helps to balance the affects of excessive physical and mental stress. When we are under a high level of stress, we often have difficulty thinking clearly and remembering things. Research studies have shown that supplementation with Tyrosine helped to improve such cognitive ability. Numerous other studies which have been conducted, proved that Tyrosine reduces anxiety and stress, and assists people to be more mentally alert.

Similarly, Tyrosine has a role in the making of "Enkephalins". These are special substances in the brain which provide pain-relieving effects to the body. They are critical to the healthy functioning of our brains, because they are responsible for transmitting nerve impulses and signals, and prevent conditions such as depression.

Additionally, this amino acid also plays a role in the regulation of blood pressure, and also helping to reduce body fat ( which significantly lowers HGH production ). Finally, it also works an AntiOxidant, helping to protect the body from damage to organs, tissues, muscles and cells caused by free radicals.

There has been much research to discover how Tyrosine stimulates the Pituitary Gland to cause it to secrete Growth Hormone. This increased release of our GH, through the work of Tyrosine, may occur at particular times, especially when under stress.

One particular study found that it has a significant part in supporting increased levels of both HGH and IGF-1, particularly in conditions of high stress or during high-intensity workouts. Researchers think that it works by activating the enzyme, called Tyrosine Kinase, which then acts in the capacity of a messenger, that the Pituitary Gland to start various metabolic activities linked to the production and release of Growth Hormone.

Furthermore, various clinical studies have demonstrated that Tyrosine is even more effective at boosting the levels of Human Growth Hormone - when it is combined with two other specific amino acids. So when Tyrosine is then combined with Arginine and Lysine, there is a greater increase in HgH levels, compared to using Tyrosine alone.

There is already much research that demonstrates elevating the levels of both Arginine and Lysine, particularly when these two amino acids are combined together, leads to a corresponding increase in the production and release of Growth Hormone.

Behavioral and Cognitive Effects of Tyrosine Intake in Healthy Human Adults

Adrian Hase; Sophie E Jung; Marije aan het Rot ( Department of Psychology, University of Groningen, Netherlands )

The amino acid Tyrosine is the precursor to the catecholamine NeuroTransmitters Dopamine and Norepinephrine. Thus, increasing the consumption of Tyrosine, can affect psychological / cognitive functions. The researchers concluded a systematic review to investigate the effects of Tyrosine on cognitive functions.

In this analysis, 15 research studies were considered. All studies except one involved using a Tyrosine load during a single test. According to their review, in most behavioral studies, there were no significant effects of Tyrosine on exercise performance. However, in contrast, research studies evaluating cognitive functions discovered that administration of Tyrosine significantly improves gradual decreases in working memory and information processing which are caused by demanding mental conditions.

The researchers concluded that the effects of Tyrosine on cognitive functioning can be understood by the ability of Tyrosine to counteract the reduced or exhausted amounts of brain catecholamines. Thus there is evidence which supports that increasing the consumption of Tyrosine may help healthy individuals experiencing demanding mental, psychological or cognitive conditions.

Working Memory Reloaded: Tyrosine Repletes Updating in the N-Back Task

Lorenza S Colzato; Bryant J Jongkees; Roberta Sellaro; Bernhard Hommel

( Institute for Psychological Research, Leiden Institute for Brain and Cognition, Leiden University, Leiden, Netherlands )

In this study, they tested the hypothesis that the amino acid Tyrosine supplies resources necessary for cognitive control operations. They evaluated if certain mental / cognitive functions, such as Working Memory ( WM ), can be improved by increasing the uptake of Tyrosine, which is the precursor of Dopamine ( DA ).

They discovered that "executive control" results from the connection between cognitive stability ( the maintenance of task-relevant representations ) and flexibility ( the ability to adapt, update, and shift between informational states ). These are two major, but partially antagonistic functions of cognitive control, which both are regulated by Dopamine.

This study concentrated on the powerful effect of supplementing with Tyrosine. They wanted to find out if Working Memory functioning, one of the most important cognitive control activities, could be improved. Their study was the first of its kind to show that the amino acid Tyrosine does promote updating of Working Memory.

And as they had anticipated, the more difficult the cognitive conditions were, the more the Working Memory updating was responsive to the effects of increasing Tyrosine. This strengthened their belief that only mental tasks with significant cognitive demands might benefit from a Tyrosine dosage. Thus, increasing levels of Tyrosine can supply the needed resources for more demanding cognitive functioning.

Tyrosine Promotes Cognitive Flexibility: Evidence From Proactive vs. Reactive Control During Task Switching Performance

Laura Steenbergen; Roberta Sellaro; Bernhard Hommel; Lorenza S Colzato

( Institute for Psychological Research, Leiden Institute for Brain and Cognition, Leiden University, Leiden, Netherlands )

The amino acid Tyrosine, found in various foods, has been shown to increase the levels of Dopamine ( DA ) in the brain. According to the researchers, recent clinical studies have produced evidence that supplementing with Tyrosine can improve various aspects of cognitive control in situations that have high cognitive demands.

This was a Double-Blind, Randomized, Placebo-Controlled Study. It involved 22 healthy adults. In this study, the researchers examined whether Tyrosine encourages flexibility in cognition. This is a major cognitive-control function that is believed to be regulated by the NeuroTransmitter Dopamine. They studied the effects of Tyrosine on proactive versus reactive control during task switching performance. This enabled them to evaluate a marker of cognitive flexibility. Here are the results.

Tyrosine improved cognitive flexibility ( the ability to switch tasks or thoughts in the brain ). This outcome supports the concept that Tyrosine can promote cognitive flexibility by supplying the required cognitive resources.

Effect of Tyrosine Supplementation on Clinical and Healthy Populations
Under Stress or Cognitive Demands - A Review

Bryant J Jongkees; Bernhard Hommel; Simone Kühn; Lorenza S Colzato

( Institute for Psychological Research, Leiden Institute for Brain and Cognition, Leiden University, Leiden, Netherlands
and Center for Lifespan Psychology, Max Planck Institute for Human Development, Berlin, Germany )

Tyrosine is the precursor of both Dopamine ( DA ) and Norepinephrine ( NE ). Increasing the amount of this amino acid may counteract decreases in neurotransmitter functions and performance in mental abilities.

In this review, they evaluated various research studies involving the use of Tyrosine on cognitive functioning / behavioral abilities. They concluded that Tyrosine does seem to positively improve cognitive performance. This is especially true during short-term stressful and / or demanding mental situations that require more cognitive resources.